Any cures for an ongoing philosophical meltdown?

Just because something isn't known yet, does not mean it can never be known. You sound like you have been reading too many aphorisms. There is no Truth out there, only a lot of little truths with small case Ts. Why are you appealing to the god of the gaps? Put down the philosophy books and pick up some science books. You've been wandering in lala land too long and need a break. Come back to the rational world.