Friday, November 11, 2011

How much does gene conversion and genetic redundancy limit the impact of deleterious mutation?

The best hope for discriminating between different possibilities lies in the fact that background selection can only affect the level of neutral variation under sharply defined conditions: greatly restricted out- breeding, or very restricted recombination over a sufficiently large genomic region that the net mutation rate to deleterious alleles is high enough to cause a low equilibrium frequency of mutation-free gametes.

No comments:

Post a Comment